Professor of applied – three dimensional CT angiography in skull base surgery in No.306 Hospital of Chinese PLA health Sohu Gu Jianwen, (the legend – the right temporal cavernous hemangioma) of skull base tumors due to its deep location, and the relationship between bone structure and irregular adjacent major blood vessels nerves and close to the skull base, revealed in the operation, separation, resection of the tumor, difficult operation, extremely easy to cause serious damage to the surrounding nerves or residual tumor caused by vascular complications. The anatomy of the skull base, the choice of surgical approach and the technique of operation are the frontiers in the field of surgery. Therefore, it is very important to fully understand the relationship between the growth of the skull base tumor and the relationship between the peripheral blood vessels and the surrounding vessels. In recent years, three dimensional spiral CT angiography (3D-SCTA) and image reconstruction techniques have been applied in clinic. Spiral CT angiography and 3D reconstruction of Three-dimensional computed tomographic angiograph by spiral CT and AW workstation software. Contrast agent for Omnipaque, the high pressure injection pump by the anterior cubital vein injection, the speed of 2.5 ~ 3.0ml s, the total amount of 80 ~ 120ml, delayed after 15 ~ 20s scan. Ball tube voltage 120kV, current 180mA. The pitch was 3.5 (half head mode), thickness of 1mm or 2mm, the scanning range is 55mm, from the foramen magnum to the level to scan, including the upper edge of the tumor and adjacent vessels. Transfer data to workstation via lan. The surface shaded display (shade surface, display, SSD), pseudo color SSD and maximum intensity projection (maximum intensity, projection, MIP) to reconstruct the 3D images, adjust the threshold to tumor blood vessels, and achieve a better display of the skull. At the same time, the 3D images were rotated, cut, and correlated with each other in order to display the three-dimensional relationship between the tumor and the adjacent vessels and the skull base. The tumor, blood vessels, 3D images of skull coated with SSD pseudo color processing, combined with the specific growth of skull base tumors neurosurgeon or violate the scope and operation requirements, rotation, cutting and measurement of 3D graphics, the best surgical approach simulation. Skull base tumors originated from the skull base bone, dura, nerves and blood vessels and glands and residual embryonic tissue, tumors can invade the intracranial pressure of brain tissue and cranial nerves, but also to extracranial growth into the sinuses, pharynx or orbital. The key to the operation of skull base tumor lies in the correct operation and correct positioning of the tumor, the reasonable choice of surgical approach and skilled microsurgical technique. In the past 30 years, the skull base Department of neurosurgery has developed rapidly, and the development of neuroimaging has played an important role in the future. Spiral CT angiography and 3D reconstruction technique can provide a more complete and comprehensive pathological information.